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Virome remodeling rewires epigenetic and metabolic pathways linked to infection-associated colorectal cancer risk

Background: Colorectal cancer (CRC) incidence is rising in sub-Saharan Africa, coinciding with the high prevalence of immune-modulating infections such as HIV and helminths. The gut virome, a critical yet understudied component of the microbiome, may influence oncogenic processes through epigenetic...

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Hlavní autoři: Botle Precious Damane, Jonathan Featherston, Shakeel Kader, Mohammed Alaouna, Pragalathan Naidoo, Zodwa Dlamini, Zilungile Lynette Mkhize-Kwitshana
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2026-06-01
Edice:Aspects of Molecular Medicine
Témata:
Colorectal cancer (CRC)
Gut virome dynamics
HIV and helminth co-infection
Epigenetic regulation
Metabolic reprogramming
Sub-Saharan Africa
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2949688826000043
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