Computational insights into pH effects on protein conformation, membrane curvature, and water permeation in the E. coli multidrug efflux transporter MdfA
Abstract Multidrug resistance (MDR) in bacteria poses a major public health challenge, driven largely by efflux transporters such as the Escherichia coli multidrug transporter MdfA. As a proton-coupled antiporter belonging to the Major Facilitator Superfamily (MFS), MdfA harnesses the transmembrane...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Springer
2026-03-01
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| Seria: | Discover Chemistry |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1007/s44371-026-00607-7 |
| Etykiety: |
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