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Development of a Topical Treatment for Psoriasis Targeting RORγ: From Bench to Skin.

<h4>Background</h4>Psoriasis is a chronic inflammatory skin disorder involving marked immunological changes. IL-17-targeting biologics have been successful in reducing the disease burden of psoriasis patients with moderate-to-severe disease. Unfortunately, the stratum corneum prevents penetration of...

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Autori principali: Susan H Smith, Carlos E Peredo, Yukimasa Takeda, Thi Bui, Jessica Neil, David Rickard, Elizabeth Millerman, Jean-Philippe Therrien, Edwige Nicodeme, Jean-Marie Brusq, Veronique Birault, Fabrice Viviani, Hans Hofland, Anton M Jetten, Javier Cote-Sierra
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2016-01-01
Serie:PLoS ONE
Accesso online:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0147979&type=printable
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