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The Enigmatic Role of C9ORF72 in Autophagy

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the loss of motor neurons resulting in a progressive and irreversible muscular paralysis. Advances in large-scale genetics and genomics have revealed intronic hexanucleotide repeat expansions in the gene...

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Bibliografische gegevens
Hoofdauteurs: Melissa Nassif, Ute Woehlbier, Patricio A. Manque
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2017-08-01
Reeks:Frontiers in Neuroscience
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Online toegang:http://journal.frontiersin.org/article/10.3389/fnins.2017.00442/full
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