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The role of autophagy in the pathogenesis and treatment of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) represent two extremes of a neurodegenerative disease spectrum characterised by overlapping genetic, clinical, and neuropathological features. This review covers the intricate relationship between both ALS and FTD and defects in t...

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Principais autores: Jimmy Beckers, Philip Van Damme
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2025-12-01
coleção:Autophagy Reports
Assuntos:
Amyotrophic lateral sclerosis (ALS)
autophagy
frontotemporal dementia (FTD)
lysosome
autophagosome
endosome
Acesso em linha:https://www.tandfonline.com/doi/10.1080/27694127.2025.2474796
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