A novel fusion protein scaffold 18/12/TxM activates the IL-12, IL-15, and IL-18 receptors to induce human memory-like natural killer cells

Natural killer (NK) cells are cytotoxic innate lymphoid cells that are emerging as a cellular immunotherapy for various malignancies. NK cells are particularly dependent on interleukin (IL)-15 for their survival, proliferation, and cytotoxic function. NK cells differentiate into memory-like cells wi...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Celia C. Cubitt, Ethan McClain, Michelle Becker-Hapak, Jennifer A. Foltz, Pamela Wong, Julia A. Wagner, Carly C. Neal, Nancy D. Marin, Lynne Marsala, Mark Foster, Timothy Schappe, Patrick Soon-Shiong, John Lee, Melissa M. Berrien-Elliott, Todd A. Fehniger
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-03-01
coleção:	Molecular Therapy: Oncolytics
Assuntos:	NK cells natural killer cells cancer cytokines memory-like NK cell N-803
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2372770522000262
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!