NK Cell IL-10 Production Requires IL-15 and IL-10 Driven STAT3 Activation

Natural killer (NK) cells can produce IFNγ or IL-10 to regulate inflammation and immune responses but the factors driving NK cell IL-10 secretion are poorly-defined. Here, we identified NK cell-intrinsic STAT3 activation as vital for IL-10 production during both systemic Listeria monocytogenes (Lm)...

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Principais autores:	Sarah E. Clark, Kristina S. Burrack, Stephen C. Jameson, Sara E. Hamilton, Laurel L. Lenz
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-09-01
coleção:	Frontiers in Immunology
Assuntos:	NK cell IL-10 Stat3 IL-15 IL-15 complex Listeria (L.) monocytogenes
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fimmu.2019.02087/full
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