Thiamine transporter 2 and Janus kinase 2 inhibitor, fedratinib suppresses thermogenic activation of human neck area-derived adipocytes
IntroductionBrown adipocytes consume higher amounts of metabolic substrates and regulators, including thiamine, during adrenergic stimulation, supporting heat generation. Our previous findings showed that fedratinib, a potent inhibitor of thiamine transporter (ThTr) 2 and Janus kinase 2 (JAK2), redu...
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| Huvudupphov: | , , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Frontiers Media S.A.
2026-02-01
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| Serie: | Frontiers in Endocrinology |
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| Länkar: | https://www.frontiersin.org/articles/10.3389/fendo.2026.1694542/full |
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