IGH rearrangements in Down syndrome acute lymphoblastic leukemia

Background: The IGH locus is susceptible to translocations or insertions that contribute to B-cell precursor acute lymphoblastic leukemia (ALL) by ectopic or enhanced expression of a gene relocated to the IGH enhancer. The frequency of IGH rearrangements is relatively high in Down syndrome (DS) ALL....

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Naomi Michels, Jade Admiraal, Aurélie Boeree, Edwin Sonneveld, Anthony V. Moorman, Gabriele Escherich, Rosemary Sutton, H. Berna Beverloo, Rob Pieters, C. Michel Zwaan, Monique L. den Boer, Judith M. Boer
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2025-06-01
Цуврал:	EJC Paediatric Oncology
Нөхцлүүд:	Fluorescence in situ hybridization Pediatric Down syndrome RNA sequencing
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2772610X25000108
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!