High coenzyme affinity chimeric amine dehydrogenase based on domain engineering
Abstract NADH-dependent phenylalanine amine dehydrogenase (F-AmDH) engineered from phenylalanine dehydrogenase (PheDH) catalyzes the synthesis of aromatic chiral amines from prochiral ketone substrates. However, its low coenzyme affinity and catalytic efficiency limit its industrial application. Her...
Sábháilte in:
| Príomhchruthaitheoirí: | , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
SpringerOpen
2022-03-01
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| Sraith: | Bioresources and Bioprocessing |
| Ábhair: | |
| Rochtain ar líne: | https://doi.org/10.1186/s40643-022-00528-0 |
| Clibeanna: |
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