Domesticated cynomolgus monkey embryonic stem cells allow the generation of neonatal interspecies chimeric pigs

Abstract Blastocyst complementation by pluripotent stem cell (PSC) injection is believed to be the most promising method to generate xenogeneic organs. However, ethical issues prevent the study of human chimeras in the late embryonic stage of development. Primate embryonic stem cells (ESCs), which h...

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Principais autores:	Rui Fu, Dawei Yu, Jilong Ren, Chongyang Li, Jing Wang, Guihai Feng, Xuepeng Wang, Haifeng Wan, Tianda Li, Libin Wang, Ying Zhang, Tang Hai, Wei Li, Qi Zhou
格式:	Artigo
語言:	Inglês
出版:	Oxford University Press 2019-11-01
叢編:	Protein & Cell
主題:	embryonic stem cells blastocyst complementation cynomolgus monkey pig interspecies chimera organ reconstruction
在線閱讀:	https://doi.org/10.1007/s13238-019-00676-8
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