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Domesticated cynomolgus monkey embryonic stem cells allow the generation of neonatal interspecies chimeric pigs

Abstract Blastocyst complementation by pluripotent stem cell (PSC) injection is believed to be the most promising method to generate xenogeneic organs. However, ethical issues prevent the study of human chimeras in the late embryonic stage of development. Primate embryonic stem cells (ESCs), which h...

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Збережено в:
Автори: Rui Fu, Dawei Yu, Jilong Ren, Chongyang Li, Jing Wang, Guihai Feng, Xuepeng Wang, Haifeng Wan, Tianda Li, Libin Wang, Ying Zhang, Tang Hai, Wei Li, Qi Zhou
Формат: Artigo
Мова:Inglês
Опубліковано: Oxford University Press 2019-11-01
Серія:Protein & Cell
Предмети:
embryonic stem cells
blastocyst complementation
cynomolgus monkey
pig
interspecies chimera
organ reconstruction
Онлайн доступ:https://doi.org/10.1007/s13238-019-00676-8
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