The Crucial Role of Demannosylating Asparagine-Linked Glycans in ERADicating Misfolded Glycoproteins in the Endoplasmic Reticulum

Most membrane and secreted proteins are glycosylated on certain asparagine (N) residues in the endoplasmic reticulum (ER), which is crucial for their correct folding and function. Protein folding is a fundamentally inefficient and error-prone process that can be easily interfered by genetic mutation...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Jianjun Zhang, Jiarui Wu, Linchuan Liu, Jianming Li
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2021-01-01
Цуврал:	Frontiers in Plant Science
Нөхцлүүд:	endoplasmic reticulum asparagine-linked glycan endoplasmic reticulum-associated degradation mannosidase protein disulfide isomerases
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fpls.2020.625033/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!