The crystal structure of the toxin EspC from enteropathogenic Escherichia coli reveals the mechanism that governs host cell entry and cytotoxicity

Enteropathogenic E. coli (EPEC) is a significant cause of diarrhea, leading to high infant mortality rates. A key toxin produced by EPEC is the EspC autotransporter, which is regulated alongside genes from the locus of enterocyte effacement (LEE), which collectively result in the characteristic atta...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Akila U. Pilapitiya, Lilian Hor, Jing Pan, Lakshmi C. Wijeyewickrema, Robert N. Pike, Denisse L. Leyton, Jason J Paxman, Begoña Heras
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Taylor & Francis Group 2025-12-01
Sarja:	Gut Microbes
Aiheet:	Enteropathogenic E. coli autotransporter protein serine protease toxins bacterial infections secretion system
Linkit:	https://www.tandfonline.com/doi/10.1080/19490976.2025.2483777
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