MicroRNA-665 facilitates cell proliferation and represses apoptosis through modulating Wnt5a/β-Catenin and Caspase-3 signaling pathways by targeting TRIM8 in LUSC

Abstract Background MicroRNAs (miRNAs) are involved in the oncogenesis, development and transformation of lung squamous cell carcinoma (LUSC). miR-665 is clinically significant and acts as a pivotal function in some cancers. Nevertheless, the effects and the potential mechanisms of miR-665 in human...

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Detalhes bibliográficos

Principais autores:	Tian-Jun Chen, Qi Zheng, Fei Gao, Tian Yang, Hui Ren, Yang Li, Ming-Wei Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-04-01
coleção:	Cancer Cell International
Assuntos:	MiR-665 TRIM8 Lung squamous cell carcinoma Proliferation Apoptosis
Acesso em linha:	https://doi.org/10.1186/s12935-021-01913-z
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