Integrated multi-omics analyses reveal Jorunnamycin A as a novel suppressor for muscle-invasive bladder cancer by targeting FASN and TOP1

Abstract Background Bladder cancer is a urological carcinoma with high incidence, among which muscle invasive bladder cancer (MIBC) is a malignant carcinoma with high mortality. There is an urgent need to develop new drugs with low toxicity and high efficiency for MIBC because existing medication ha...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Ruijiao Chen, Xiaopeng Hao, Jingyuan Chen, Changyue Zhang, Huixia Fan, Fuming Lian, Xiaochuan Chen, Chao Wang, Yong Xia
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2023-08-01
Serija:	Journal of Translational Medicine
Teme:	Jorunnamycin A Muscle invasive bladder cancer Proteomics Transcriptomics Proliferation Apoptosis
Online dostop:	https://doi.org/10.1186/s12967-023-04400-3
Oznake:	Označite Brez oznak, prvi označite!