Inverse FASN and LDHA correlation drives metabolic resistance in breast cancer

Abstract Background Breast cancer manifests as a heterogeneous pathology marked by complex metabolic reprogramming essential to satisfy its energy demands. Oncogenic signals boost the metabolism, modifying fatty acid synthesis and glucose use from the onset to progression and therapy resistant-forms...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Chiara Papulino, Ugo Chianese, Ahmad Ali, Gregorio Favale, Concetta Tuccillo, Fortunato Ciardiello, Annabella Di Mauro, Chiara Mignogna, Gerardo Ferrara, Alfredo Budillon, Wouter Leonard Megchelenbrink, Nunzio Del Gaudio, Mariarosaria Conte, Fabrizio Merciai, Pietro Campiglia, Lucia Altucci, Vincenzo Carafa, Eduardo Sommella, Rosaria Benedetti
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-07-01
Edice:	Journal of Translational Medicine
Témata:	Breast cancer FASN LDHA Metabolism Tamoxifen resistance
On-line přístup:	https://doi.org/10.1186/s12967-024-05517-9
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!