Integrated multi-omics analyses reveal Jorunnamycin A as a novel suppressor for muscle-invasive bladder cancer by targeting FASN and TOP1

Abstract Background Bladder cancer is a urological carcinoma with high incidence, among which muscle invasive bladder cancer (MIBC) is a malignant carcinoma with high mortality. There is an urgent need to develop new drugs with low toxicity and high efficiency for MIBC because existing medication ha...

Полное описание

Библиографические подробности

Главные авторы:	Ruijiao Chen, Xiaopeng Hao, Jingyuan Chen, Changyue Zhang, Huixia Fan, Fuming Lian, Xiaochuan Chen, Chao Wang, Yong Xia
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2023-08-01
Серии:	Journal of Translational Medicine
Предметы:	Jorunnamycin A Muscle invasive bladder cancer Proteomics Transcriptomics Proliferation Apoptosis
Online-ссылка:	https://doi.org/10.1186/s12967-023-04400-3
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!