Astragaloside-IV Protects Against Heat-induced Apoptosis by Inhibiting Excessive Activation of Mitochondrial Ca2+ Uniporter

Background: Heat causes airway damage during inhalation injury because of bronchial epithelial cell damage. Accumulating evidence shows that mitochondrial uniporter (MCU) is involved in cell damage. We investigated the MCU activity after heat treatment and assessed whether Astragaloside-IV (AS-IV) s...

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Bibliografische Detailangaben

Hauptverfasser:	Zhiwei Dong, Chen Zhang, Yajie Chen, Yu Chen, Zhiqiang Yuan, Yizhi Peng, Tongtong Cao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cell Physiol Biochem Press GmbH & Co KG 2017-06-01
Schriftenreihe:	Cellular Physiology and Biochemistry
Schlagworte:	Astragaloside-IV Heat injury MCU Ca2+ overload ROS Apoptosis
Online-Zugang:	http://www.karger.com/Article/FullText/477595
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