Clinical considerations for the treatment of patients with familial chylomicronemia syndrome using a hepatic-targeted APOC3 antisense oligonucleotide

Familial chylomicronemia syndrome (FCS) is a rare, typically debilitating genetic disorder of extreme hypertriglyceridemia associated with high triglyceride levels and elevated risk for recurrent acute pancreatitis. Diagnosis of FCS is frequently delayed due to its rarity, and treatment options are...

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Detalhes bibliográficos

Principais autores:	Archna Bajaj, Elif A. Oral, Alan Brown, Daniel Gaudet, Veronica J. Alexander, Ewa Karwatowska-Prokopczuk, Seth J. Baum
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-12-01
coleção:	American Journal of Preventive Cardiology
Assuntos:	Familial chylomicronemia syndrome Hypertriglyceridemia Olezarsen Antisense oligonucleotide Apolipoprotein C-III Acute pancreatitis
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2666667725004271
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