Clinical considerations for the treatment of patients with familial chylomicronemia syndrome using a hepatic-targeted APOC3 antisense oligonucleotide

Familial chylomicronemia syndrome (FCS) is a rare, typically debilitating genetic disorder of extreme hypertriglyceridemia associated with high triglyceride levels and elevated risk for recurrent acute pancreatitis. Diagnosis of FCS is frequently delayed due to its rarity, and treatment options are...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Archna Bajaj, Elif A. Oral, Alan Brown, Daniel Gaudet, Veronica J. Alexander, Ewa Karwatowska-Prokopczuk, Seth J. Baum
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2025-12-01
Schriftenreihe:	American Journal of Preventive Cardiology
Schlagworte:	Familial chylomicronemia syndrome Hypertriglyceridemia Olezarsen Antisense oligonucleotide Apolipoprotein C-III Acute pancreatitis
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2666667725004271
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