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Opportunities, challenges, and future perspectives of oncolytic virus therapy for malignant melanoma

Malignant melanoma is characterized by high heterogeneity, aggressive metastatic potential, and a profoundly immunosuppressive “cold” tumor microenvironment, contributing to broad therapeutic resistance and suboptimal responses to immunotherapy. Conventional PD-1 inhibitors yield an ORR of only 38%....

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Sábháilte in:
Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Jia-Wen Wang, Qi Feng, Jia-Hui Liu, Jian-Jun Xun
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Frontiers Media S.A. 2025-09-01
Sraith:Frontiers in Immunology
Ábhair:
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1653683/full
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