Pseudomonas aeruginosa-derived extracellular vesicles enhance macrophage aerobic glycolysis that fuels inflammation

Outer membrane vesicles (OMVs) derived from Pseudomonas aeruginosa drive inflammation by metabolically reprogramming macrophages to favor aerobic glycolysis. This study shows that OMVs trigger this metabolic shift via Toll-like receptors 2 and 4 (TLR2/4)-dependent activation of the phosphoinositide...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Chun Li, Jing Peng, Lihua Xiao, Haiying Wu, Jing Chen, Nian Chen
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2025-07-01
Цуврал:	Frontiers in Microbiology
Нөхцлүүд:	Pseudomonas aeruginosa aerobic glycolysis toll-like receptor outer membrane vesicle inflammation
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fmicb.2025.1619101/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!