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Pseudomonas aeruginosa-derived extracellular vesicles enhance macrophage aerobic glycolysis that fuels inflammation

Outer membrane vesicles (OMVs) derived from Pseudomonas aeruginosa drive inflammation by metabolically reprogramming macrophages to favor aerobic glycolysis. This study shows that OMVs trigger this metabolic shift via Toll-like receptors 2 and 4 (TLR2/4)-dependent activation of the phosphoinositide...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Chun Li, Jing Peng, Lihua Xiao, Haiying Wu, Jing Chen, Nian Chen
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2025-07-01
Rangatū:Frontiers in Microbiology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1619101/full
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