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Tumour cells can escape antiproliferative pressure by interferon-β through immunoediting of interferon receptor expression

Abstract Type I interferons (IFNs) play a central role not only in innate immunity against viral infection, but also in the antitumour response, e.g. through a direct impact on cell proliferation. Particularly for cancer arising in the context of chronic inflammation, constant exposure to IFNs may c...

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Principais autores: Felix Hiebinger, Aiste Kudulyte, Huanting Chi, Sebastian Burbano De Lara, Doroteja Ilic, Barbara Helm, Hendrik Welsch, Viet Loan Dao Thi, Ursula Klingmüller, Marco Binder
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-12-01
coleção:Cancer Cell International
Assuntos:
Interferon
Immunoediting
Cell proliferation
Signalling
Interferon resistance
Cancer
Acesso em linha:https://doi.org/10.1186/s12935-023-03150-y
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