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A Monte Carlo-based framework enhances the discovery and interpretation of regulatory sequence motifs

<p>Abstract</p> <p>Background</p> <p>Discovery of functionally significant short, statistically overrepresented subsequence patterns (motifs) in a set of sequences is a challenging problem in bioinformatics. Oftentimes, not all sequences in the set contain a motif. These non-motif-containing sequenc...

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Autores principales: Seitzer Phillip, Wilbanks Elizabeth G, Larsen David J, Facciotti Marc T
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2012-11-01
Colección:BMC Bioinformatics
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Acceso en línea:http://www.biomedcentral.com/1471-2105/13/317
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