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Global mapping of binding sites for phic31 integrase in transgenic maden-darby bovine kidney cells using ChIP-seq

Abstract Background ΦC31 integrase, a site-specific recombinase, can efficiently target attB-bearing transgenes to endogenous pseudo attP sites within mammalian genomes. The sequence features of endogenous binding sites will help us to fully understand the site-specific recognition function by ΦC31...

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Hlavní autoři: Lijuan Qu, Lei Wang, Xueyuan Zhu, Yan Zhang, Qiang Ou, Aying Ma, Fengying Sheng, Xiaoqing Wei, Yue Dai, Guoting Li, Shuwu Xie
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2019-01-01
Edice:Hereditas
Témata:
ΦC31 integrase
Binding sites
ChIP-seq
Sequence motif
On-line přístup:http://link.springer.com/article/10.1186/s41065-018-0079-z
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