Combatting sepsis-induced myocardial dysfunction: emerging mechanisms and immunomodulatory breakthroughs

Sepsis-induced myocardial dysfunction (SIMD) critically contributes to mortality in systemic inflammatory responses, driven by multifaceted mechanisms including dysregulated inflammation, immunosuppression, oxidative stress, and autonomic dysfunction. Emerging pathways involve m6A RNA methylation (m...

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Detalhes bibliográficos

Principais autores:	Can Liu, Hanfeng Liu, Yunxing Li, Yangxi Zeng, Xinyu Wang, Yuhan Mou, Bin Liao, Juyi Wan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-11-01
Colecção:	Frontiers in Immunology
Assuntos:	sepsis myocardial injury inflammation sepsis-induced myocardial dysfunction targeted therapy
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1643048/full
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