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Combatting sepsis-induced myocardial dysfunction: emerging mechanisms and immunomodulatory breakthroughs

Sepsis-induced myocardial dysfunction (SIMD) critically contributes to mortality in systemic inflammatory responses, driven by multifaceted mechanisms including dysregulated inflammation, immunosuppression, oxidative stress, and autonomic dysfunction. Emerging pathways involve m6A RNA methylation (m...

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Principais autores: Can Liu, Hanfeng Liu, Yunxing Li, Yangxi Zeng, Xinyu Wang, Yuhan Mou, Bin Liao, Juyi Wan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-11-01
Serier:Frontiers in Immunology
Fag:
sepsis
myocardial injury
inflammation
sepsis-induced myocardial dysfunction
targeted therapy
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1643048/full
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