Identfication of Potent LXRβ-Selective Agonists without LXRα Activation by In Silico Approaches
Activating Liver X receptors (LXRs) represents a promising therapeutic option for dyslipidemia. However, activating LXRα may cause undesired lipogenic effects. Discovery of highly LXRβ-selective agonists without LXRα activation were indispensable for dyslipidemia. In this study, in...
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| Автори: | , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
MDPI AG
2018-06-01
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| Серія: | Molecules |
| Предмети: | |
| Онлайн доступ: | http://www.mdpi.com/1420-3049/23/6/1349 |
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