Genome-wide risk prediction of common diseases across ancestries in one million people

Summary: Polygenic risk scores (PRS) measure genetic disease susceptibility by combining risk effects across the genome. For coronary artery disease (CAD), type 2 diabetes (T2D), and breast and prostate cancer, we performed cross-ancestry evaluation of genome-wide PRSs in six biobanks in Europe, the...

全面介紹

書目詳細資料

Principais autores:	Nina Mars, Sini Kerminen, Yen-Chen A. Feng, Masahiro Kanai, Kristi Läll, Laurent F. Thomas, Anne Heidi Skogholt, Pietro della Briotta Parolo, Benjamin M. Neale, Jordan W. Smoller, Maiken E. Gabrielsen, Kristian Hveem, Reedik Mägi, Koichi Matsuda, Yukinori Okada, Matti Pirinen, Aarno Palotie, Andrea Ganna, Alicia R. Martin, Samuli Ripatti
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2022-04-01
叢編:	Cell Genomics
主題:	polygenic risk score health disparities global health ancestry precision medicine risk prediction
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2666979X22000428
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!