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GSK-3β phosphorylation of functionally distinct tau isoforms has differential, but mild effects

<p>Abstract</p> <p>Background</p> <p>Tau protein exists as six different isoforms that differ by the inclusion or exclusion of exons 2, 3 and 10. Exon 10 encodes a microtubule binding repeat, thereby resulting in three isoforms with three microtubule binding repeats (3R) and three isoforms that have...

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Bibliografski detalji
Glavni autori: Gamblin T Chris, Voss Kellen
Format: Artigo
Jezik:Inglês
Izdano: BMC 2009-05-01
Serija:Molecular Neurodegeneration
Online pristup:http://www.molecularneurodegeneration.com/content/4/1/18
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