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Association between type III collagen degradation and local tissue damage of a single joint

Objective: The development of disease-modifying drugs is limited by OA's heterogeneity and the challenge of defining clinical endpoints. Serological biomarkers are considered potential surrogate endpoints, but their contribution from single joints to systemic levels in OA patients is unclear. In thi...

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Autori principali: Christian S. Thudium, Sten Rasmussen, Morten A. Karsdal, Anne-Christine Bay-Jensen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2024-12-01
Serie:Osteoarthritis and Cartilage Open
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Accesso online:http://www.sciencedirect.com/science/article/pii/S2665913124000943
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