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The fibroid phenotype of biological naïve patients with rheumatoid arthritis are less likely to respond to anti-IL-6R treatment

Abstract Type III collagen gene expression is upregulated in the synovium of patients with rheumatoid arthritis (RA) presenting the fibroid phenotype. The soluble type III collagen formation biomarker, PRO-C3, is known to measure fibrogenesis in fibrotic diseases. In this exploratory study, we aimed...

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Detalhes bibliográficos
Principais autores: Sofie Falkenløve Madsen, Dovile Sinkeviciute, Christian S. Thudium, Morten A. Karsdal, Anne-Christine Bay-Jensen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2024-05-01
Colecção:Scientific Reports
Acesso em linha:https://doi.org/10.1038/s41598-024-61435-2
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