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Constitutive secretion of tau protein by an unconventional mechanism

The microtubule-associated protein tau plays a critical role in the pathogenesis of Alzheimer's disease and several related disorders. In the disease tau aggregates into paired helical and straight filaments, which can form higher order neurofibrillary tangles in neurons and this pathology is associ...

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Bibliografische gegevens
Hoofdauteurs: Xiyun Chai, Jeffrey L. Dage, Martin Citron
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2012-12-01
Reeks:Neurobiology of Disease
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Online toegang:http://www.sciencedirect.com/science/article/pii/S0969996112002070
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