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Overview of epigenetic degraders based on PROTAC, molecular glue, and hydrophobic tagging technologies

Epigenetic pathways play a critical role in the initiation, progression, and metastasis of cancer. Over the past few decades, significant progress has been made in the development of targeted epigenetic modulators (e.g., inhibitors). However, epigenetic inhibitors have faced multiple challenges, inc...

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Váldodahkkit: Xiaopeng Peng, Zhihao Hu, Limei Zeng, Meizhu Zhang, Congcong Xu, Benyan Lu, Chengpeng Tao, Weiming Chen, Wen Hou, Kui Cheng, Huichang Bi, Wanyi Pan, Jianjun Chen
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Elsevier 2024-02-01
Ráidu:Acta Pharmaceutica Sinica B
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Liŋkkat:http://www.sciencedirect.com/science/article/pii/S2211383523003556
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