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A third copy of the Down syndrome cell adhesion molecule (Dscam) causes synaptic and locomotor dysfunction in Drosophila

Down syndrome (DS) is caused by triplication of chromosome 21 (HSA21). It is characterised by intellectual disability and impaired motor coordination that arise from changes in brain volume, structure and function. However, the contribution of each HSA21 gene to these various phenotypes and to the c...

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書誌詳細
主要な著者: Simon A. Lowe, James J.L. Hodge, Maria M. Usowicz
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2018-02-01
シリーズ:Neurobiology of Disease
主題:
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S0969996117302747
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