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A third copy of the Down syndrome cell adhesion molecule (Dscam) causes synaptic and locomotor dysfunction in Drosophila

Down syndrome (DS) is caused by triplication of chromosome 21 (HSA21). It is characterised by intellectual disability and impaired motor coordination that arise from changes in brain volume, structure and function. However, the contribution of each HSA21 gene to these various phenotypes and to the c...

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Detalles Bibliográficos
Principais autores: Simon A. Lowe, James J.L. Hodge, Maria M. Usowicz
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2018-02-01
Series:Neurobiology of Disease
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S0969996117302747
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