Defining the regulatory logic of breast cancer using single-cell epigenetic and transcriptome profiling

Summary: Annotation of cis-regulatory elements that drive transcriptional dysregulation in cancer cells is critical to understanding tumor biology. Herein, we present matched chromatin accessibility (single-cell assay for transposase-accessible chromatin by sequencing [scATAC-seq]) and transcriptome...

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Detalhes bibliográficos

Principais autores:	Matthew J. Regner, Susana Garcia-Recio, Aatish Thennavan, Kamila Wisniewska, Raul Mendez-Giraldez, Brooke Felsheim, Philip M. Spanheimer, Joel S. Parker, Charles M. Perou, Hector L. Franco
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-02-01
coleção:	Cell Genomics
Assuntos:	breast cancer enhancer elements gene regulation chromatin accessibility scRNA-seq scATAC-seq
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2666979X25000217
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