Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells.

HIV infection has a profound effect on "bystander" cells causing metabolic co-morbidities. This may be mediated by exosomes secreted by HIV-infected cells and containing viral factors. Here we show that exosomes containing HIV-1 protein Nef (exNef) are rapidly taken up by macrophages releasing Nef i...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Nigora Mukhamedova, Anh Hoang, Dragana Dragoljevic, Larisa Dubrovsky, Tatiana Pushkarsky, Hann Low, Michael Ditiatkovski, Ying Fu, Ryunosuke Ohkawa, Peter J Meikle, Anelia Horvath, Beda Brichacek, Yury I Miller, Andrew Murphy, Michael Bukrinsky, Dmitri Sviridov
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Public Library of Science (PLoS) 2019-07-01
Sarja:	PLoS Pathogens
Linkit:	https://escholarship.org/uc/item/8sf0738d
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