Discontinuous EBOV RNA synthesis events in patients with Ebola virus disease and their relationship to viral load and outcome of infection

ABSTRACT Ebola virus (EBOV) is a negative strand RNA virus that causes Ebola virus disease (EVD) with a high case fatality rate. During the acute phase of infection, a subsequent fatal outcome is characterized by an increased upregulation of interferon and inflammatory pathways compared to survivors...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Xiaofeng Dong, Isabel Garcia-Dorival, Natasha Y. Rickett, Andrew Bosworth, Sophie Smither, Stuart Dowall, Miles W. Carroll, David A. Matthews, Thomas R. Laws, Paul Digard, Julian A. Hiscox
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2025-12-01
Edice:	Journal of Virology
Témata:	defective genomes Ebola viral replication transcriptomics Ebola virus
On-line přístup:	https://journals.asm.org/doi/10.1128/jvi.00826-25
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!