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Novel cancer treatment paradigm targeting hypoxia-induced factor in conjunction with current therapies to overcome resistance

Abstract Chemotherapy, radiotherapy, targeted therapy, and immunotherapy are established cancer treatment modalities that are widely used due to their demonstrated efficacy against tumors and favorable safety profiles or tolerability. Nevertheless, treatment resistance continues to be one of the mos...

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Principais autores: Ting-Wan Kao, Geng-Hao Bai, Tian-Li Wang, Ie-Ming Shih, Chi-Mu Chuang, Chun-Liang Lo, Meng-Chen Tsai, Li-Yun Chiu, Chu-Chien Lin, Yao-An Shen
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-07-01
Serier:Journal of Experimental & Clinical Cancer Research
Fag:
Hypoxia
HIF-1
HIF-2
Chemotherapy
Target therapy
Radiotherapy
Online adgang:https://doi.org/10.1186/s13046-023-02724-y
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