Tumor acidification and GSH depletion by bimetallic composite nanoparticles for enhanced chemodynamic therapy of TNBC

Abstract Chemodynamic therapy (CDT) based on intracellular Fenton reaction to produce highly cytotoxic reactive oxygen species (ROS) has played an essential role in tumor therapy. However, this therapy still needs to be improved by weakly acidic pH and over-expression of glutathione (GSH) in tumor m...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Wenting Chen, Fangfang Hu, Qian Gao, Caiyun Zheng, Que Bai, Jinxi Liu, Na Sun, Wenhui Zhang, Yanni Zhang, Kai Dong, Tingli Lu
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2024-03-01
Sarja:	Journal of Nanobiotechnology
Aiheet:	Chemodynamic therapy Reactive oxygen species Gallic acid Fenton reaction Metal-polyphenol networks
Linkit:	https://doi.org/10.1186/s12951-024-02308-8
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