Protective Efficacy of Lyophilized Vesicular Stomatitis Virus–Based Vaccines in Animal Model

We evaluated the in vitro effects of lyophilization for 2 vesicular stomatitis virus–based vaccines by using 3 stabilizing formulations and demonstrated protective immunity of lyophilized/reconstituted vaccine in guinea pigs. Lyophilization increased stability of the vaccines, but specific vesicula...

Descripció completa

Dades bibliogràfiques

Autors principals:	Abd’jeleel Salawudeen, Geoff Soule, Nikesh Tailor, Levi Klassen, Jonathan Audet, Angela Sloan, Yvon Deschambault, David Safronetz
Format:	Artigo
Idioma:	Inglês
Publicat:	Centers for Disease Control and Prevention 2024-05-01
Col·lecció:	Emerging Infectious Diseases
Matèries:	vesicular stomatitis virus vaccines Ebola virus Lassa virus glycoproteins lyophilized
Accés en línia:	https://wwwnc.cdc.gov/eid/article/30/5/23-1248_article
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!