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Protective Efficacy of Lyophilized Vesicular Stomatitis Virus–Based Vaccines in Animal Model

We evaluated the in vitro effects of lyophilization for 2 vesicular stomatitis virus–based vaccines by using 3 stabilizing formulations and demonstrated protective immunity of lyophilized/reconstituted vaccine in guinea pigs. Lyophilization increased stability of the vaccines, but specific vesicula...

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Wedi'i Gadw mewn:
Prif Awduron: Abd’jeleel Salawudeen, Geoff Soule, Nikesh Tailor, Levi Klassen, Jonathan Audet, Angela Sloan, Yvon Deschambault, David Safronetz
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Centers for Disease Control and Prevention 2024-05-01
Cyfres:Emerging Infectious Diseases
Pynciau:
vesicular stomatitis virus
vaccines
Ebola virus
Lassa virus
glycoproteins
lyophilized
Mynediad Ar-lein:https://wwwnc.cdc.gov/eid/article/30/5/23-1248_article
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