Subcellular Compartmentalization of Glucose Mediated Insulin Secretion

Regulation of blood glucose levels depends on the property of beta cells to couple glucose sensing with insulin secretion. This is accomplished by the concentration-dependent flux of glucose through glycolysis and oxidative phosphorylation, generating ATP. The resulting rise in cytosolic ATP/ADP inh...

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Autors principals:	Zhongying Wang, Tatyana Gurlo, Leslie S. Satin, Scott E. Fraser, Peter C. Butler
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-01-01
Col·lecció:	Cells
Matèries:	compartmentalization submembrane beta cells K<sub>ATP</sub> channel mitochondria oxidative phosphorylation
Accés en línia:	https://www.mdpi.com/2073-4409/14/3/198
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