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Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays.

<h4>Background</h4>Promoter and 5' end methylation regulation of tumour suppressor genes is a common feature of many cancers. Such occurrences often lead to the silencing of these key genes and thus they may contribute to the development of cancer, including prostate cancer.<h4>Methodology/principal...

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Principais autores: Ken Kron, Vaijayanti Pethe, Laurent Briollais, Bekim Sadikovic, Hilmi Ozcelik, Alia Sunderji, Vasundara Venkateswaran, Jehonathan Pinthus, Neil Fleshner, Theodorus van der Kwast, Bharati Bapat
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2009-01-01
coleção:PLoS ONE
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19283074/?tool=EBI
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