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Characterizing primary transcriptional responses to short term heat shock in Down syndrome.

Heat shock stress induces genome-wide changes in transcription regulation, activating a coordinated cellular response to enable survival. We noticed many heat shock genes are up-regulated in blood samples from individuals with trisomy 21. We characterized the immediate transcriptional response to he...

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書誌詳細
主要な著者: Joseph F Cardiello, Jessica Westfall, Robin Dowell, Mary Ann Allen
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2024-01-01
シリーズ:PLoS ONE
オンライン・アクセス:https://doi.org/10.1371/journal.pone.0307375
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