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Mature tertiary lymphoid structures support B cell-mediated antitumour immunity and are disrupted by neoadjuvant therapy in rectal cancer: a multicentre, retrospective studyResearch in context

Summary: Background: The tumour immune microenvironment (TIME), particularly the presence and maturation of tertiary lymphoid structures (TLS), shapes antitumour immunity and therapy response. However, the role of mature TLS (mTLS) in rectal cancer (RC) and their modulation by neoadjuvant therapy (...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Na Tian, Qianyu Wang, Yuan Lv, Wentao Zhong, Weixuan Li, Huiyun Cai, Ran An, Hongyan Zhu, Liang Sun, Qiang Yuan, Xing Dong, Junhua Dong, Junchao Bai, Aijun Liu, Gang Chen, Bin Wu, Junfeng Du
التنسيق: Artigo
اللغة:Inglês
منشور في: Elsevier 2025-12-01
سلاسل:EBioMedicine
الموضوعات:
الوصول للمادة أونلاين:http://www.sciencedirect.com/science/article/pii/S2352396425004748
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