Polyoxometalate inhibition of SOX2-mediated tamoxifen resistance in breast cancer

Abstract Background Increased cancer stem cell (CSC) content and SOX2 overexpression are common features in the development of resistance to therapy in hormone-dependent breast cancer, which remains an important clinical challenge. SOX2 has potential as biomarker of resistance to treatment and as th...

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Үндсэн зохиолчид:	Iskander Aurrekoetxea-Rodriguez, So Young Lee, Miriam Rábano, Isabel Gris-Cárdenas, Virginia Gamboa-Aldecoa, Irantzu Gorroño, Isabella Ramella-Gal, Connor Parry, Robert M. Kypta, Beñat Artetxe, Juan M. Gutierrez-Zorrilla, Maria dM. Vivanco
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2024-09-01
Цуврал:	Cell Communication and Signaling
Нөхцлүүд:	Breast cancer Cancer stem cells Resistance Hormone therapy SOX2 inhibition Polyoxometalate
Онлайн хандалт:	https://doi.org/10.1186/s12964-024-01800-w
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